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Ruptured / Leaking Abdominal Aortic Aneurysm
Ruptured AAA has a prehospital mortality of ~50% and 30-day surgical mortality of 40%. The classic triad is sudden severe back/abdominal pain, pulsatile epigastric mass, and haemodynamic instability — but only 25–50% present with all three…
Vascular Society UK / NICE NG156
The pathway
1 · Recognise and activate vascular team immediately
- Do NOT wait for imaging if the patient is haemodynamically unstable with suspected AAA
- Call vascular surgery consultant directly — not via switchboard
- Alert anaesthetics, theatre, and radiology simultaneously
- Classic triad: sudden severe back/flank/abdominal pain + pulsatile mass + shock
- In stable patients: bedside aortic USS for rapid confirmation (avoid CT delay in unstable)
2 · Permissive hypotension — key concept
- Restrictive volume resuscitation (permissive hypotension) — NICE NG156 gives no numeric target. Aim for a patient who stays conscious and mentating, and follow the regional vascular protocol
- Do NOT give large fluid boluses — raises BP → displaces tamponade → increases bleeding
- Max 500ml crystalloid boluses only if losing consciousness
- O-negative blood if cross-match unavailable and transfusion essential
- No GTN, no antihypertensives
- Move to theatre faster rather than normalise BP
3 · Bloods and MHP
- Group and save / crossmatch 10 units PRBCs — immediately
- Activate Major Haemorrhage Protocol (MHP): PRBCs : FFP : platelets in 1:1:1 ratio
- FBC, coag, U&E, glucose, VBG, lactate
- 2 large-bore IV cannulae + arterial line (if time allows)
- Tranexamic acid 1g IV over 10 minutes — give early
4 · CT aortogram — for haemodynamically stable patients only
- If SBP >80 and haemodynamically stable → CT aortogram (chest-abdomen-pelvis with contrast)
- Provides: confirmation of rupture, anatomy for EVAR planning, assessment of iliac vessels
- Do NOT take unstable patient to CT — direct to theatre
- Brief the CT radiologist: urgent aneurysm query, potential EVAR
5 · EVAR vs Open Repair decision
- EVAR (Endovascular Aneurysm Repair): preferred if anatomy suitable (infrarenal neck ≥15mm, adequate iliac access)
- Lower 30-day mortality than open, faster, less blood loss
- Not available at all centres — transfer if needed (only if stable)
- Open repair: if anatomy unsuitable for EVAR, EVAR equipment/expertise unavailable, or juxta/suprarenal rupture
- Retroperitoneal approach: preferred for ruptured AAA (better proximal control)
- Decision: vascular surgeon + vascular interventional radiologist
6 · Intraoperative and post-operative care
- Aortic cross-clamp → immediate haemostasis in open repair
- Hypothermia: warm IV fluids, warming blanket, warm theatre
- Lethal triad: hypothermia + coagulopathy + acidosis — aggressive correction
- Post-op ITU: organ support, bowel ischaemia surveillance (elevated lactate, bloody NG), AKI very common
- Endoleak surveillance post-EVAR: CT at 1 month, then 1 year
Drugs
| Drug | Dose | Route | Notes |
|---|---|---|---|
| Tranexamic acid | 1g IV over 10 minutes | IV | Give early in suspected haemorrhage. Second dose 1g IV at 3 hours if ongoing bleeding. |
| O-negative PRBCs | 2–4 units | IV | Uncrossmatched blood if actively dying before crossmatch available. Switch to crossmatched blood ASAP. |
| FFP (Fresh Frozen Plasma) | 4 units per 4 units PRBC | IV | 1:1:1 ratio with PRBCs and platelets via MHP. Corrects coagulopathy. |
| Cryoprecipitate | 2 pools (10 units) | IV | If fibrinogen <1.5 g/L (target >1.5 g/L). Activated via MHP. |
| Calcium gluconate 10% | 10–20ml IV | IV | Massive transfusion chelates calcium — replace every 4 units of blood products. |
| 0.9% NaCl | 500ml bolus (cautious) | IV | Minimal fluid pre-operatively — restrictive resuscitation, titrated to consciousness rather than to a number. NICE NG156 sets no target SBP. Avoid large-volume resuscitation. |
When to escalate
SBP <50 or GCS falling — immediate theatre regardless of imaging, open aortic cross-clamp,Anatomy unsuitable for EVAR at local centre and patient stable enough — emergency transfer to EVAR-capable vascular centre,Post-op rising lactate or bloody NG — bowel ischaemia; emergency laparotomy and bowel viability assessment,Post-op AKI — renal replacement therapy via ITU; contrast-induced + hypoperfusion injury,Endoleak post-EVAR (early) — interventional radiology for embolisation or secondary procedure,Haemodynamic collapse on table — consider aortic balloon occlusion (REBOA) if available as bridge
Reference: Vascular Society UK Ruptured AAA Guidelines / NICE NG156 Abdominal Aortic Aneurysm 2020
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