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Ruptured / Leaking Abdominal Aortic Aneurysm

Ruptured AAA has a prehospital mortality of ~50% and 30-day surgical mortality of 40%. The classic triad is sudden severe back/abdominal pain, pulsatile epigastric mass, and haemodynamic instability — but only 25–50% present with all three…

Vascular Society UK / NICE NG156

The pathway

1 · Recognise and activate vascular team immediately

2 · Permissive hypotension — key concept

3 · Bloods and MHP

4 · CT aortogram — for haemodynamically stable patients only

5 · EVAR vs Open Repair decision

6 · Intraoperative and post-operative care

Drugs

DrugDoseRouteNotes
Tranexamic acid1g IV over 10 minutesIVGive early in suspected haemorrhage. Second dose 1g IV at 3 hours if ongoing bleeding.
O-negative PRBCs2–4 unitsIVUncrossmatched blood if actively dying before crossmatch available. Switch to crossmatched blood ASAP.
FFP (Fresh Frozen Plasma)4 units per 4 units PRBCIV1:1:1 ratio with PRBCs and platelets via MHP. Corrects coagulopathy.
Cryoprecipitate2 pools (10 units)IVIf fibrinogen <1.5 g/L (target >1.5 g/L). Activated via MHP.
Calcium gluconate 10%10–20ml IVIVMassive transfusion chelates calcium — replace every 4 units of blood products.
0.9% NaCl500ml bolus (cautious)IVMinimal fluid pre-operatively — restrictive resuscitation, titrated to consciousness rather than to a number. NICE NG156 sets no target SBP. Avoid large-volume resuscitation.

When to escalate

SBP <50 or GCS falling — immediate theatre regardless of imaging, open aortic cross-clamp,Anatomy unsuitable for EVAR at local centre and patient stable enough — emergency transfer to EVAR-capable vascular centre,Post-op rising lactate or bloody NG — bowel ischaemia; emergency laparotomy and bowel viability assessment,Post-op AKI — renal replacement therapy via ITU; contrast-induced + hypoperfusion injury,Endoleak post-EVAR (early) — interventional radiology for embolisation or secondary procedure,Haemodynamic collapse on table — consider aortic balloon occlusion (REBOA) if available as bridge

Reference: Vascular Society UK Ruptured AAA Guidelines / NICE NG156 Abdominal Aortic Aneurysm 2020

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