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Surgical sieve

🌡️ Fever

Find the source: chest, urine, abdomen, skin, lines, CNS, joints. Then think beyond infection.

Sepsis of any source Must exclude NEWS ≥5, tachycardia, hypotension, confusion, raised lactate.Sepsis 6 within 1 hour.
Neutropenic sepsis Must exclude Any fever within 6 weeks of chemotherapy. May have no other signs.Antibiotics within 1 hour — do not wait for the neutrophil count.
Meningitis Must exclude Headache, photophobia, neck stiffness, non-blanching rash.Antibiotics immediately; do not delay for LP or CT.
Malaria Must exclude Any fever with travel to an endemic area in the last year.Thick and thin films within 1 hour; three sets to exclude.
Infective endocarditis Time-sensitive Fever with a new murmur. Splinter haemorrhages, embolic phenomena.Three sets of blood cultures from different sites, echo.
Line or catheter infection Time-sensitive Look at every line site. Fever with no other source in an inpatient.Inspect and consider removing the line; peripheral + line cultures.
Pneumonia Time-sensitive Cough, focal chest signs, hypoxia.
Urinary tract infection / pyelonephritis Time-sensitive Dysuria, loin pain, vomiting.
Intra-abdominal collection Time-sensitive Post-operative swinging fever. Often days 5–7 post-op.CT abdomen; may need drainage.
Cellulitis / necrotising fasciitis Time-sensitive Nec fasc: pain out of proportion, rapidly spreading, systemic toxicity, crepitus.Mark the margin. Nec fasc is a surgical emergency.
Venous thromboembolism Time-sensitive PE and DVT can both cause a low-grade fever.
Drug fever / transfusion reaction Time-sensitive Temporal relationship to a new drug or blood product.Stop the transfusion; review recent drug changes.
Malignancy Consider Lymphoma, renal cell carcinoma. Night sweats, weight loss.
Inflammatory / autoimmune Consider Vasculitis, connective tissue disease, adult Still's disease.

14 differentials · 11 open a full pathway in the app.

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