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🤕 Headache

Thunderclap, fever, focal signs, or new in the over-50s? Those are the ones that matter.

Subarachnoid haemorrhage Must exclude Thunderclap — maximal within seconds. Neck stiffness, vomiting, photophobia.CT head within 6h; LP at 12h for xanthochromia if CT negative.
Meningitis / encephalitis Must exclude Fever, photophobia, neck stiffness, rash, confusion.Antibiotics ± aciclovir immediately.
Raised intracranial pressure / mass Must exclude Worse on waking or lying flat, worse on coughing, vomiting, papilloedema.CT head. Avoid LP before imaging.
Giant cell arteritis Must exclude Over 50, new headache, scalp tenderness, jaw claudication, visual symptoms.Visual symptoms → IV methylprednisolone immediately, before biopsy.
Intracranial haemorrhage Must exclude Focal signs, reduced GCS. Low threshold if anticoagulated.CT within 1h if anticoagulated.
Venous sinus thrombosis Time-sensitive Progressive headache, seizures, focal signs. Pregnancy, dehydration, thrombophilia.CT/MR venogram.
Acute angle-closure glaucoma Time-sensitive Painful red eye, hazy cornea, fixed mid-dilated pupil, halos, vomiting.Same-hour ophthalmology; acetazolamide + pilocarpine.
CO poisoning Time-sensitive Whole household affected, better away from home. Saturations falsely normal.COHb on co-oximetry, 100% oxygen.
Hypertensive emergency Time-sensitive Very high BP with headache, visual change, papilloedema, encephalopathy.
Migraine Common Unilateral, throbbing, photophobia, aura, previous identical episodes.A first "migraine" over 50 needs more thought.
Tension headache Common Bilateral, band-like, no red flags, normal examination.
Medication overuse or withdrawal Consider Analgesia >15 days/month. Caffeine or opioid withdrawal.
Sinusitis Consider Facial pain, worse leaning forward, nasal discharge. Watch for orbital spread.

13 differentials · 8 open a full pathway in the app.

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